A Chronically Implantable Bidirectional Neural Interface for Non-human Primates

A Chronically Implantable Bidirectional Neural Interface for Non-human Primates

Optogenetics has potential applications in the study of epilepsy and neuroprostheses, and for studies on neural circuit dynamics. However, to achieve translation to clinical usage, optogenetic interfaces that are capable of chronic stimulation and monitoring with minimal brain trauma are required. We aimed to develop a chronically implantable device for photostimulation of the brain of non-huma...

A Wireless 32-Channel Implantable Bidirectional Brain Machine Interface

All neural information systems (NIS) rely on sensing neural activity to supply commands and control signals for computers, machines and a variety of prosthetic devices. Invasive systems achieve a high signal-to-noise ratio (SNR) by eliminating the volume conduction problems caused by tissue and bone. An implantable brain machine interface (BMI) using intracortical electrodes provides excellent ...

A system for recording neural activity chronically and simultaneously from multiple cortical and 1 subcortical regions in non - human primates

Shaping the Dynamics of a Bidirectional Neural Interface

Progress in decoding neural signals has enabled the development of interfaces that translate cortical brain activities into commands for operating robotic arms and other devices. The electrical stimulation of sensory areas provides a means to create artificial sensory information about the state of a device. Taken together, neural activity recording and microstimulation techniques allow us to e...

Non-human Primates

Introduction Less than 1⁄4 of one percent of all lab animals needed in the U.S. are non-human primates. Approximately 30 different species are studied by the research community.1 Many historic scientific breakthroughs, such as the discovery of the Rh factor and the development of a live polio virus vaccine were achieved through research with non-human primates. Today they are considered extreme...